The Florida State Seminoles take on the Clemson Tigers in Clemson, South Carolina, on Saturday, Nov. 8. Kickoff is set for 7 p.m. ET on ACC Network.
Clemson is favored by 1.5 points on the spread with a moneyline of -120. Florida State, meanwhile, enters as a +1.5 underdog and is +100 on the moneyline to pull off the upset. The over/under sits at 56 total points.
Here’s my Florida State vs. Clemson prediction and college football picks for Saturday, November 8.
Florida State vs Clemson Prediction, Pick
- Florida State vs. Clemson Pick: Florida State 1H ML (+100)
My Clemson vs. Florida State best bet is on the Seminoles to be leading at halftime. Find the best line available on our live NCAAF odds page.
Florida State vs Clemson Odds, Spread, Lines
| Florida State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -110 | 56 -115o / -115u | +100 |
| Clemson Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -110 | 56 -115o / -115u | -120 |
- Florida State vs Clemson Spread: Clemson -1.5, Florida State +1.5
- Florida State vs Clemson Over/Under: 56 Points
- Florida State vs Clemson Moneyline: Florida State +100, Clemson -120
Florida State Seminoles vs Clemson Tigers Preview
Why Florida State Can Cover
The Seminoles have the opportunity to prove themselves offensively. They're a rush-heavy offense led by running back Gavin Sawchuk and quarterback Tommy Castellanos.
Those two have combined to make Florida State a sneaky-good offense, as the Seminoles come into this game ranked 21st in yards per rush.
However, their high rush volume and effectiveness have also allowed Castellanos to beat opposing defenses over the top. He ranks eighth in yards per pass on only 27 attempts per game.
While Clemson's defense is a stout test on paper, we've seen it give up points in bunches to the likes of Duke, SMU and Syracuse.
Look for the Seminoles to control the clock with their run game and stretch the field when the Tigers load the box.
Why Clemson Can Cover
This season has been a massive disappointment for the Tigers, and they're beginning to free-fall.
Head coach Dabo Sweeney is publicly criticizing officiating amid a two-game losing streak, and they need to win three of their final four games to reach bowl eligibility after beginning the year ranked fourth in the country.
Their inability to run the ball has made life harder for quarterback Cade Klubnik. The Tigers rank 81st in yards per rush and have been predictable on offense, passing the ball at the 20th-highest rate in the country.
Here, they'll be up against a Florida State defense that has held its own against the likes of Miami and Alabama. The Seminoles rank 16th in yards per rush allowed, and their defensive front has also disrupted the pass, ranking 18th in sack rate.

How To Make Florida State vs Clemson Picks
There hasn't been much market movement from a full-game perspective, but the first half shows that the Seminoles are very live in this matchup.
They have the edge on both sides of the ball, and given Clemson's current form, their home-field advantage is minimal.
Back Florida State to lead this one at halftime.
Pick: Florida State 1H ML (+100)



















