The Ole Miss Rebels take on the Michigan State Spartans in the Sweet 16. Tip-off is set for 7:09 p.m. ET on CBS.
Michigan State is favored by 3.5 points on the spread, with a moneyline of -180. The total is set at 144.5 points.
Here are my Ole Miss vs. Michigan State predictions and college basketball picks for March 28, 2025.
Ole Miss vs Michigan State Prediction
My Pick: Michigan State -5 or Better
My Ole Miss vs Michigan State best bet is on the Spartans spread, with the best odds currently available at DraftKings. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Ole Miss vs Michigan State Odds
| Ole Miss Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+3.5 -115 | 144.5 -110o / -110u | +150 |
| Michigan State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-3.5 -105 | 144.5 -110o / -110u | -180 |
- Ole Miss vs Michigan State spread: Michigan State -3.5
- Ole Miss vs Michigan State over/under: 144.5 points
- Ole Miss vs Michigan State moneyline: Michigan State -180, Ole Miss +150
- Ole Miss vs Michigan State best bet: Michigan State -5 or Better
My Ole Miss vs Michigan State NCAAB Betting Preview
Tom Izzo is synonymous with winning in March. He's been to eight Final Fours, placing him among the royalty of college basketball's coaching circles.
In the Sweet 16, he'll face one of the rising stars of college coaches, Chris Beard. Beard has been a head coach for nine seasons, already racking up 13 NCAA Tournament wins, three trips to the second weekend and a Final Four appearance.
In that time, Beard's teams are 12-6 ATS in the Big Dance and notably, 8-1 ATS in the first game of a tournament weekend when given time to prepare.
Beard's team will certainly be ready for Sparty, but not just due to the coaching staff. The Ole Miss roster is the third-most experienced in all college basketball, per KenPom, and the most experienced remaining in the field.
Every significant member of the Rebels has played at least three seasons of college hoops, with three fifth-year seniors in the rotation.
