LA Galaxy vs. Columbus Odds & Betting Predictions - April 22, 2026

LA Galaxy at Columbus

11:30 pm

LA Galaxy

5-5-4

1

1 - 2

Columbus Crew

3-7-4

2

MatchupOpenSpreadTotalMoneyline
LA Galaxy 5-5-4	+1.5	+1.5-250	o3.5+130	+360
Columbus 3-7-4	u3.5	-1.5+182	u3.5-161	-155

location pin

Wednesday 11:30 p.m.

April 22, 2026

ScottsMiracle-Gro FieldColumbus, OH

MLS Public Betting

Columbus are 0-2 in their last 5 games.
Columbus are 0-4 in their last 5 games against the spread
Columbus are 1-6 in their road games against the spread
The totals have gone OVER in 3 of Columbus' last 5 games
The totals have gone OVER in 1 of Columbus' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Columbus	2-11-1	1-5	1-6-1	2-10	0-1-1
LA Galaxy	8-6	3-3	5-3	2-4	6-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Columbus	8-6	1-5	7-1	7-5	1-1
LA Galaxy	8-6	3-3	5-3	4-2	4-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Columbus	3-7	2-2-2	1-5-2	3-6-3	0-1-1
LA Galaxy	5-5	2-2-2	3-3-2	2-3-1	3-2-3

date	opponent	score	spread	over/under	moneyline
Apr 18th	@NE	L 1-2	-0.5 L	O 2.5	NE +123
Apr 12th	ORL	W 1-1	-1.5 L	U 3.5	ORL -232
Apr 4th	@ATL	W 3-1	-0.5 W	O 2.5	CLB +125
Mar 21st	@TOR	L 1-2	-0.5 L	O 2.5	TOR +125
Mar 14th	NSH	L 0-1	-0.5 L	U 2.5	NSH -165

Douglas Costa
MID
Metatarsal Fracture
Out Indefinitely
R. Alessandrini
MID
MCL Knee Ligament Injury
Out Indefinitely
N. DePuy
DEF
DePuy is injured
Out Indefinitely

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LA Galaxy

Columbus

5

Fouls

13

4

Shots

10

1

Corners

4

1

Offsides

1

0

Red Cards

0

1

Yellow Cards

0

1

Shots On Goal

5

41%

Possession Time

59%

LA Galaxy

Goalkeeping

Columbus

Could not load odds

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MatchupOverUnder
LA Galaxy 5-5-4	N/A	N/A
Columbus 3-7-4	N/A	N/A