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Michigan vs. USC Odds & Betting Predictions - October 11, 2025

Michigan at USC

11:30 pm • NBC

Michigan Wolverines

4-1
@

USC Trojans

4-1

Michigan at USC Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Michigan
4-1
-1.5
+2.5-106
o57.5-110
+114
USC
4-1
u50.5
-2.5-114
u57.5-110
-135
location pinSaturday 11:30 p.m.
October 11, 2025
Los Angeles Memorial ColiseumLos Angeles
thermometer image78°Fahrenheit
rain image0%Rain
wind image6Wind
Michigan vs. USC Expert Picks
Picks Office
Picks Office
Last 30d: 60-70-2 (-6.4u)
Over 56-110
1u
X:PicksOffice
Boomer Betz
Boomer Betz
Last 30d: 129-112-2 (+28.4u)
USC -126
1u
Babs .
Babs .
Last 30d: 76-75-0 (+1.9u)
MICH -1+125
1u
Stuck 🚨
Stuck 🚨
Last 30d: 47-54-2 (-0.5u)
USC -2.5-104
0.5u
Collin Wilson
Collin Wilson
Last 30d: 80-62-1 (+3.4u)
Over 55.5-110
1.1u
Project 67; USC allowing too many explosive on the ground, outside T100 defensive rush efficiency v Underwood/Haynes. Michigan defense outside T50 v pass explosives, 91st defensive finishing drives

Prop Odds Comparison

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No props found

Line Movement Tracker

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Michigan vs. USC Public Betting Percentages

Away Logo

Michigan

Public

Home Logo

USC

18%

Bets%

82%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • USC are 4-1 in their last 5 games.
  • USC are 2-3 in their last 5 games against the spread
  • USC are 0-2 in their road games against the spread
  • The totals have gone OVER in 4 of USC' last 5 games
  • The totals have gone OVER in 3 of USC' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
USC		2-32-10-22-3N/A
Michigan		2-31-21-12-20-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
USC		4-13-01-14-1N/A
Michigan		3-22-11-13-10-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
USC		4-1N/AN/A4-1N/A
Michigan		4-1N/AN/A4-00-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 27th@ILLL 32-34-6.5 LO 62ILL -250
Sep 21stMSUW 45-31-18.5 LO 55.5USC -950
Sep 13th@PURW 33-17-20.5 LU 59.5USC -1600
Sep 6thGASOW 59-20-29 WO 62.5USC -7000
Aug 30thMOSTW 73-13-36.5 WO 60USC -9000
Team Stats

Passing

1003
YDS
1690
77/131
Comps/Atts
111/154
7.66
YPA
10.97
3/1
TDs/INTs
12/1
5/20
Sacks/Yards
4/28

Rushing

1189
Rush Yards
1135
186
Attempts
177
6.39
YPC
6.41
17
TDs
17

Turnovers

Fumbles Lost
1
Interceptions
1

Efficiency

16/19 84.2%
Redzone
28/29 96.6%
26/62 0%
3rd Down
31/55 0%
1/5 0%
4th Down
9/11 0%

First Downs

102
Total
133
46
Pass
72
51
Rush
49
5
Penalty
12

Misc

/
Penalties/Yards
/

Michigan vs. USC Odds Comparison

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Michigan at USC Team Totals

MatchupOverUnder
Michigan
4-1
N/A
N/A
USC
4-1
N/A
N/A