In a battle between 3-0 teams, No. 1 Ohio State travels to Seattle to take on Washington on Saturday afternoon.
The Buckeyes are coming off a bye week while the Huskies just dropped 59 points on their Pacific Northwest rival Washington State.
Let's dive into the Washington vs. Ohio State odds and my college football picks for Week 5.
Washington vs Ohio State Odds, Line
Washington Odds | ||
---|---|---|
Spread | Total | Moneyline |
+8 -110 | 53.5 -105o / -115u | +270 |
Ohio State Odds | ||
---|---|---|
Spread | Total | Moneyline |
-8 -110 | 53.5 -105o / -115u | -340 |


Washington vs Ohio State Pick, Parlay
- Ohio State ML -315
- CJ Donaldson to Score a TD (-120)
Parlay Payout: +120 (via bet365)

Moneyline Pick: Ohio State ML -315
The first-ranked Buckeyes will have a test on the road on Saturday.
Following its National Championship, Ohio State has impressed early in 2025, most notably in a victory over then-first-ranked Texas.
While I expect this game to be closer than most people think, the Buckeyes will come out on top.
Ryan Day's team holds a significant advantage in the trenches on both sides of the football.
I expect a rush-heavy attack from the Buckeyes and for them to control the tempo of this matchup, stringing together long and productive drives while keeping Washington’s offense on the sidelines.
Ohio State will avoid the upset on Saturday.

Ohio State Player Prop Pick: CJ Donaldson Anytime TD
I believe CJ Donaldson will see a heavy workload on Saturday.
Washington has been great against the run, but it hasn't faced an offensive line like Ohio State's or a back like Donaldson.
The West Virginia transfer has been the top option in the backfield for the Bucks, leading the team with 33 attempts.
Donaldson is the Buckeyes' goal-line back and should earn multiple opportunities to find the end zone in Seattle.