Best College Football Upset Picks, Moneyline Predictions for Saturday Week 2

Best College Football Upset Picks, Moneyline Predictions for Saturday Week 2 article feature image
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Caleb Douglas #5 of the Texas Tech Red Raiders (Photo by John E. Moore III/Getty Images)

Our upset-minded college football PRO System recommended three picks last week. Not only did all three underdogs win outright, frankly, they weren't even remotely close at any point:

  • Coastal Carolina (55-27)
  • Eastern Michigan (28-14)
  • UNLV (27-7)

Make that 3-0 for roughly +4.5 units. The reads are certainly on point to kick things off.

Riding the hot hand, that same PRO System pinpointed even more Week 2 college football upset picks, revealing five underdogs to consider locking in for Saturday's games.

Some of our PRO Systems involve a whole bunch of filters. The moneyline bets below, meanwhile, stem from an extremely straightforward strategy.

Let's analyze a whole host of picks primed to upset their opponents on Saturday of Week 2, based on previous, key insights.


College Football Week 2 Upset Predictions and Picks Saturday

There's a method to how our PRO System picks the underdogs.

It has absolutely nothing — and I mean this sincerely, literally zero — to do with matchup, X's and O's, how jacked the strength coordinators are for either team, whatever.

Rather, our system simply factors in the betting line, the over/under and home-road splits. All three underdogs last week won by a combined score of 110-48. Is that good?

If you're wondering when to target upsets in college football, here's a tip: When the road team is +4 or tighter against the spread, and the over/under is