Cubs vs. White Sox Odds & Betting Predictions - May 16, 2026

Cubs at White Sox

11:10 pm • MARQ
@
Starting Pitchers
pitcherteameraw-l
Davis Martin logoD.MartinChicago White Sox logo1.625-1
Jameson Taillon logoJ.TaillonChicago Cubs logo3.942-2

Cubs at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
29-16
+1.5
-1.5+155
o8.5-111
-110
White Sox
22-22
u8.5
+1.5-180
u8.5-108
-110
location pinSaturday 11:10 p.m.
May 16, 2026
Rate FieldChicago
thermometer image81°Fahrenheit
rain image0%Rain
wind image6Wind
Cubs vs. White Sox Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 265-350-21 (+3.4u)
Under 4.5 (F5)-109
0.84u
#EV 1.55%
Mike McNamara
Mike McNamara
Last 30d: 15-42-0 (-2.0u)
CWS -110
0.11u
Grant Neiffer
Grant Neiffer
Last 30d: 33-109-9 (+9.7u)
M.Vargas o0.5 HR+464
0.25u
RoyalsProps
RoyalsProps
Last 30d: 72-57-5 (+9.9u)
C.Montgomery o1.5 Hits + Runs + RBIs-108
1.08u
Frank Ammirante
Frank Ammirante
Last 30d: 292-285-7 (+17.8u)
M.Murakami o0.5 HR+290
0.1u
CWS -120 (F5)
1.2u

Cubs vs. White Sox Previews & Analysis

  • The Leadoff: Trollo's MLB Breakdown & Bets for Saturday article feature image

    The Leadoff: Trollo's MLB Breakdown & Bets for Saturday

    Matt Trollo
    May 16, 2026 UTC
  • Cubs vs White Sox: PRO's Prop Edge for Saturday article feature image

    Cubs vs White Sox: PRO's Prop Edge for Saturday

    Action Network Staff
    May 16, 2026 UTC
  • Grant's 2 Best Home Run Bets for Saturday article feature image

    Grant's 2 Best Home Run Bets for Saturday

    Grant Neiffer
    May 16, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. White Sox Public Betting Percentages

Away Logo

Cubs

Public

54%

Bets%

46%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
25-1913-912-102-323-16
Cubs
21-2412-119-1314-157-9

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
25-1912-1013-93-222-17
Cubs
25-2013-1012-1015-1410-6

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
22-2212-1010-122-320-19
Cubs
29-1618-511-1121-88-8

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 15thCHCL 5-10+1.5 LO 8.5CHC +106
May 14thKCW 6-2+1.5 WU 8CWS +114
May 13thKCW 6-5+1.5 WO 8CWS -105
May 12thKCW 6-5+1.5 WO 9.5CWS -105
May 10thSEAW 2-1+1.5 WU 8CWS +118

White Sox vs. Cubs Injury Updates

White Sox Injuries

  • Mike Vasil
    RP

    Vasil is out with elbow

    Out

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Brooks Baldwin
    LF

    Baldwin is out with elbow

    Out

  • Kyle Teel
    C

    Teel is out with hamstring

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

  • Jordan Wicks
    SP

    Wicks is out with arm

    Out

Cubs vs. White Sox Starting Lineups
Cubs Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Jameson Taillon logoRJ.Taillon, P2-23.941.1397.88
HITTERSAVGOBPSLGHR
Nico Hoerner logo1N.Hoerner, SS.264.340.3994
Michael Busch logo2M.Busch, 1B.231.352.3563
Alex Bregman logo3A.Bregman, 3B.250.338.3584
Ian Happ logo4I.Happ, DH.241.381.48110
Seiya Suzuki logo5S.Suzuki, RF.272.382.4917
Michael Conforto logo6M.Conforto, LF.333.441.6042
Matt Shaw logo7M.Shaw, 2B.256.306.4223
Pete Crow-Armstrong logo8P.Crow-Armstrong, CF.236.308.3644
Miguel Amaya logo9M.Amaya, C.230.365.3442
White Sox Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Davis Martin logoRD.Martin, P5-11.621.0009.36
HITTERSAVGOBPSLGHR
Sam Antonacci logo1S.Antonacci, LF.274.380.4171
Munetaka Murakami logo2M.Murakami, 1B.227.368.52615
Miguel Vargas logo3M.Vargas, 3B.247.376.49410
Colson Montgomery logo4C.Montgomery, SS.237.335.51912
Chase Meidroth logo5C.Meidroth, 2B.277.352.3943
Andrew Benintendi logo6A.Benintendi, DH.216.268.3362
Jarred Kelenic logo7J.Kelenic, RF.250.341.3611
Tristan Peters logo8T.Peters, CF.260.315.3200
Drew Romo logo9D.Romo, C.200.364.6004

Cubs vs. White Sox Odds Comparison

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Cubs at White Sox Team Totals

MatchupOverUnder
Cubs
29-16
N/A
N/A
White Sox
22-22
N/A
N/A