Cubs vs. Pirates Odds & Betting Predictions - May 28, 2026

Cubs at Pirates

10:40 pm • MARQ
@
Starting Pitchers
pitcherteameraw-l
Paul Skenes logoP.SkenesPittsburgh Pirates logo3.006-4
Colin Rea logoC.ReaChicago Cubs logo4.834-3

Cubs at Pirates Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
30-26
+1.5
+1.5-151
o7.5-108
+145
Pirates
29-27
u7.5
-1.5+125
u7.5-111
-174
location pinThursday 10:40 p.m.
May 28, 2026
PNC ParkPittsburgh
thermometer image68°Fahrenheit
rain image0%Rain
wind image9Wind
Cubs vs. Pirates Expert Picks
Grant Neiffer
Grant Neiffer
Last 30d: 27-110-8 (+2.9u)
B.Lowe o0.5 HR+475
0.25u
💰🦡 Jake
💰🦡 Jake
Last 30d: 55-59-5 (+6.7u)
PIT o4.5+115
1u
RoyalsProps
RoyalsProps
Last 30d: 64-43-4 (+17.0u)
B.Lowe o1.5 Hits + Runs + RBIs-125
1.25u
Frank Ammirante
Frank Ammirante
Last 30d: 218-240-11 (-8.8u)
P.Skenes u1.5 BB-150
1.5u
B.Reynolds o0.5 HR+750
0.1u
PIT -0.5 (F5)-130
1.3u
Brandon Kravitz
Brandon Kravitz
Last 30d: 73-91-2 (-13.0u)
Over 7.5-101
1.01u

Cubs vs. Pirates Previews & Analysis

  • Slugfest! 6 2B/HR Picks for MLB Thursday article feature image

    Slugfest! 6 2B/HR Picks for MLB Thursday

    Alex Kolodziej
    May 28, 2026 UTC
  • Frank's Pick for Cubs vs Pirates article feature image

    Frank's Pick for Cubs vs Pirates

    Frank Ammirante
    May 28, 2026 UTC
  • The Leadoff: Trollo's MLB Breakdown and Bets for Thursday article feature image

    The Leadoff: Trollo's MLB Breakdown and Bets for Thursday

    Matt Trollo
    May 28, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Pirates Public Betting Percentages

Away Logo

Cubs

Public

26%

Bets%

74%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Pirates
30-2615-1415-1217-1412-12
Cubs
22-3412-1710-1714-228-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Pirates
29-25-218-1111-14-219-129-13-2
Cubs
31-2515-1416-1118-1813-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Pirates
29-2715-1414-1318-1310-14
Cubs
30-2618-1112-1521-159-11

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 27thCHCL 4-10-1.5 LO 9CHC -125
May 26thCHCW 12-1-1.5 WO 8PIT -138
May 25thCHCW 2-1+1.5 WU 8.5PIT +105
May 24th@TORW 4-1+1.5 WU 7.5PIT +145
May 23rd@TORL 2-5-1.5 LU 7.5TOR -144

Pirates vs. Cubs Injury Updates

Pirates Injuries

  • Jared Jones
    SP

    Jones is out with elbow

    Out

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

Cubs vs. Pirates Starting Lineups
Cubs Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Colin Rea logoRC.Rea, P4-34.831.3707.33
HITTERSAVGOBPSLGHR
Pete Crow-Armstrong logo1P.Crow-Armstrong, CF.224.314.3636
Nico Hoerner logo2N.Hoerner, 2B.256.341.3704
Michael Busch logo3M.Busch, 1B.232.366.3896
Alex Bregman logo4A.Bregman, 3B.261.343.3604
Ian Happ logo5I.Happ, LF.215.346.43611
Seiya Suzuki logo6S.Suzuki, RF.234.331.3967
Moises Ballesteros logo7M.Ballesteros, DH.236.314.4236
Miguel Amaya logo8M.Amaya, C.234.352.3773
Dansby Swanson logo9D.Swanson, SS.190.292.3467
Pirates Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Paul Skenes logoRP.Skenes, P6-43.000.8179.75
HITTERSAVGOBPSLGHR
Spencer Horwitz logo1S.Horwitz, 1B.288.388.4626
Brandon Lowe logo2B.Lowe, 2B.269.355.56014
Bryan Reynolds logo3B.Reynolds, LF.266.385.4024
Nick Gonzales logo4N.Gonzales, 3B.297.351.3460
Oneil Cruz logo5O.Cruz, CF.260.324.45311
Konnor Griffin logo6K.Griffin, SS.261.322.3944
Marcell Ozuna logo7M.Ozuna, DH.186.271.3025
Jake Mangum logo8J.Mangum, RF.250.324.2720
Henry Davis logo9H.Davis, C.139.238.2784

Cubs vs. Pirates Odds Comparison

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Cubs at Pirates Team Totals

MatchupOverUnder
Cubs
30-26
N/A
N/A
Pirates
29-27
N/A
N/A