The Pittsburgh Pirates (6-4) host the San Diego Padres (5-5) on April 7, 2026. First pitch from PNC Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on SportsNet PT.
The Pirates are favored by -154 on the moneyline and by -1.5 (+150) on the run line. The Padres are +130 on the moneyline and +1.5 (-182) on the run line. The total is set at 6.5 runs (+100o / -122u).
Find my MLB picks and Padres vs Pirates prediction below, as well as probable pitchers, weather report, and more.
Padres vs Pirates Predictions, Pick
- Padres vs Pirates Pick: Under 6 (+100 or Better)
My Padres vs Pirates best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Pirates Odds, Spread, Line
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -182 | 6.5 100o / -122u | +130 |
| Pirates Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +150 | 6.5 100o / -122u | -154 |
- Padres vs Pirates spread: Pirates -1.5 (+150), Padres +1.5 (-182)
- Padres vs Pirates over/under: 6.5 (-100 / -122)
- Padres vs Pirates moneyline: Padres +130, Pirates -154
Padres vs Pirates Probable Pitchers
| Nick Pivetta (RHP) | Stat | Paul Skenes (RHP) |
|---|---|---|
| 1-1 | W-L | 1-1 |
| 0.3 | fWAR (FanGraphs) | 0.1 |
| 6.75 / 3.36 | ERA / xERA | 9.53 / 2.35 |
| 2.05 / 4.64 | FIP / xFIP | 3.71 / 6.15 |
| 1.63 | WHIP | 1.94 |
| 18.9% | K-BB% | 6.9% |
| 53.8% | GB% | 27.8% |
| 103 | Stuff+ | 100 |
| 98 | Location+ | 104 |
Padres vs Pirates MLB Betting Preview
How To Make Padres vs Pirates Picks, Betting Analysis
The Pirates don't play until Tuesday evening, but conditions will be similarly suppressive for offense at PNC Park, with 43 degrees at first pitch and mid-30s by midgame.
The wind is blowing out to right field, which reduced my downward projected weather adjustment.
However, I would still have made this game around 7 on a weather-neutral day and set it closer to 5.75 with an excellent pitching matchup in cold weather.
Pick: Under 6 (+100 or Better)
