The Cleveland Guardians (23-21) host the Los Angeles Angels (16-27) on May 13, 2026. First pitch from Progressive Field is scheduled for 1:10 p.m. EDT. The game will be broadcast on CLEG.
The Guardians are favored by -156 on the moneyline and by -1.5 (+130) on the run line. The Angels are +132 on the moneyline and +1.5 (-160) on the run line. The total is set at 7 runs (-110 / -110).
Find my MLB picks and Angels vs Guardians prediction below, as well as probable pitchers, weather report, and more.
Angels vs Guardians Predictions, Pick
- Angels vs Guardians Pick: Guardians ML (play to -170)
My Angels vs Guardians best bet is on Cleveland to win outright. Make sure to find the best odds by checking our live MLB odds page.
Angels vs Guardians Odds, Run Line, Over/Under
| Angels Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -160 | 7 -110o / -110u | +132 |
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +130 | 7 -110o / -110u | -156 |
- Angels vs Guardians moneyline: Angels +132, Guardians -156
- Angels vs Guardians over/under: 7 (-110 / -110)
- Angels vs Guardians spread: Angels +1.5 (-160), Guardians -1.5 (+130)
Angels vs Guardians Probable Pitchers
| LHP Reid Detmers (LAA) | Stat | LHP Parker Messick (CLE) |
|---|---|---|
| 1-3 | W-L | 4-1 |
| 1.2 | fWAR (FanGraphs) | 1.4 |
| 4.33 / 2.90 | ERA / xERA | 2.30 / 3.06 |
| 3.09 / 3.84 | FIP / xFIP | 2.82 / 2.97 |
| 17.0% | K-BB% | 22.2% |
| 38.8% | GB% | 46.6% |
| .300 | BABIP | 2.74 |
| 105 | Stuff+ | 98 |
| 110 | Location+ | 109 |
Angels vs Guardians MLB Picks, Props
Los Angeles Angels
It’s been another tough start for the Angels, who sit nine games below .500 and fourth in the American League West.
The Angels will give the ball to starter turned reliever back to starter, Reid Detmers. Detmers owns a 4.33 ERA, which isn't great, but his 2.90 xERA and 3.33 FIP are positive indicators for future success.
Opponents are hitting .214 against Detmers and barrel him up just 5.8% of the time. He also sports a 9.69 K/9 and a 3.09 BB/9, topped off with a pristine 0.62 HR/9.
All the Angels' shaky offense could muster on Tuesday was two runs, one coming from a Vaughn Grissom eighth-inning homer. I just despise teams that don't draw walks and punch out a ton. Sadly, that applies to the Angels, who own a 25% strikeout rate (third worst) and a 6.8% walk rate (2nd worst) since April 22nd.
In those 18 games, the Angels are 19th in wRC+, and Mike Trout is their only player with a wRC+ better than 119. Trout is doing his thing, hitting for power, drawing walks, and helping out this porous offense. Nolan Schanuel and Jo Adell are hitting close to .300, but both have a walk rate below 2%. That limits their overall offensive production.
The good news for the Angels? Trout is healthy. That's all the good news I can find for this team right now.
Cleveland Guardians
The Guardians did it again. They found another stud pitcher, this time it's southpaw Parker Messick, who'll oppose Detmers. Messick enters Wednesday's outing with a 2.30 ERA, a 3.06 xERA, and a 2.82 FIP.
Messick has a baseball savant page that is glowing red. He generates weak contact, as he ranks in the 90th percentile in barrel rate, to go with his 84th percentile ranking in strikeout and walk rate. Usually, if you don't walk hitters and induce weak contact, it'll lead to strong results. That gives me plenty of confidence in Messick handling his business here.
After a hot offensive start, the Guardians have dipped to 22nd with a 93 wRC+ since April 22nd. Their approach is admirable; they strike out just 18% of the time and walk 12% of the time. The lack of offensive talent caps their ceiling, but putting the ball in play and walking will give them a decent floor most nights.
The more concerning issue is that Steven Kwan and Jose Ramirez look like a shell of their former All-Star selves. Ramirez is hitting .211 this year and .191 with a 59 wRC+ in his last 18 games. He still has an OBP over .300, but he isn't doing damage. The same applies to Kwan. So, if two of the top three hitters in this Guardians order are hitting well below .200 for almost a month, that's a worry.
Still, I think Cleveland could be a top-15 offense if Kwan and Ramirez turn a corner.
How To Bet My Angels vs Guardians Pick, Best Bet
I see value in Cleveland at anything below -170. The pitching matchup favors them, even with Detmers likely seeing some positive regression. I just don't see how the Angels score off of Messick. He could tally a bunch of strikeouts and make this scuffling offense appear foolish.
All it takes is for Cleveland to clog the bases, maybe hit one ball out, and it should cruise to another win.
Pick: Guardians ML (play to -170)
