The Chicago White Sox host the Kansas City Royals on May 13, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on ROYL.
The Royals are favored by -112 on the moneyline and by -1.5 on the run line. The White Sox are -104 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Royals vs White Sox prediction below, as well as probable pitchers, weather report, and more.
Royals vs White Sox Picks:
Royals vs White Sox Odds
| Royals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +146 | 8 -110o / -110u | -112 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -176 | 8 -110o / -110u | -104 |
Royals vs White Sox Probable Pitchers
| Seth Lugo (RHP, KCR) | Stat | Noah Schultz (LHP, CHW) |
|---|---|---|
| 1-2 | W-L | 2-2 |
| 1.5 | fWAR (FanGraphs) | 0.4 |
| 3.21 / 4.46 | ERA / xERA | 4.68 / 4.24 |
| 2.70 / 3.90 | FIP / xFIP | 4.24 / 4.83 |
| 12.8% | K-BB% | 6.6% |
| 37.8% | GB% | 33.3% |
| .346 | BABIP | .231 |
| 88 | Stuff+ | 99 |
| 107 | Location+ | 98 |
Royals vs White Sox MLB Betting Preview
The Royals are set to square off with the White Sox on Wednesday night in what will be the second of a three-game set at Guaranteed Rate Field in Chicago.
Kansas City right-handed pitcher Seth Lugo will take the mound for the visiting Royals, while White Sox Southpaw Noah Schultz will be on the bump for Chicago.
Schultz has had a very up-and-down start to his first year in the Big Leagues, and is currently running a 4.68 ERA and 1.32 WHIP. I have faith in his long-term upside because of his 22% strikeout rate and versatile arsenal, but I’m concerned about his control and command of that arsenal.
Kansas City’s lineup is not in the best form either — the Royals have lost three of their past five.

Royals vs White Sox Pick, Betting Analysis
While the lineup has mostly struggled, Bobby Witt Jr. has started to find his rhythm in the batter’s box, and I think he’s got a good matchup against Schultz.
If Schultz fails to establish his four-seam fastball early, he will likely be forced to resort to his off-speed arsenal, which includes a sweeper, sinker, and change-up. And given Schultz's lack of command over his past three outings, I expect the Sox left-hander to face a lot of problems matched up with an elite contact hitter with tremendous patience.
Ultimately, I’m banking on Witt causing chaos on the basepaths.
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