The Pittsburgh Pirates host the Cincinnati Reds on June 28, 2026. First pitch from PNC Park is scheduled for 1:35 p.m. EDT. The game will be broadcast on SportsNet PT.
The Pirates are favored by -132 on the moneyline and by -1.5 on the run line. The Reds are +112 on the moneyline and +1.5 on the run line. The total is set at 9 runs.
Find my MLB picks and Reds vs Pirates prediction below, as well as probable pitchers, weather report, and more.
Reds vs Pirates Prediction
- Reds vs Pirates Pick: Elly De La Cruz Over 1.5 HRR (-160)
My Reds vs Pirates best bet is on Elly De La Cruz. Make sure to find the best odds by checking our live MLB odds page.
Reds vs Pirates Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -205 | 9 -104o / -118u | +112 |
| Pirates Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +168 | 9 -104o / -118u | -132 |
- Reds vs Pirates moneyline: Reds +112, Pirates -132
- Reds vs Pirates over/under: 9 (-104 / -118)
- Reds vs Pirates spread: Pirates -1.5 (+168), Reds +1.5 (-205)
Reds vs Pirates Probable Pitchers
| Brady Singer (RHP, CIN) | Stat | Mitch Keller (RHP, PIT) |
|---|---|---|
| 3-6 | W-L | 5-5 |
| 0.0 | fWAR (FanGraphs) | 1.2 |
| 4.81 / 5.47 | ERA / xERA | 4.89 / 4.93 |
| 5.75 / 4.59 | FIP / xFIP | 4.16 / 4.46 |
| 10.3% | K-BB% | 9.8% |
| 41.4% | GB% | 38.9% |
| .305 | BABIP | .289 |
| 91 | Stuff+ | 93 |
| 97 | Location+ | 102 |
Reds vs Pirates MLB Betting Preview
The Pirates will host the Reds on Sunday afternoon in the last of a three-game homestand at PNC Park in Pittsburgh. 30-year-old right-hander Mitch Keller will take the mound for the Pirates, while the Reds plan to trot out righty Brady Singer.
In what has been a very up-and-down 2026 campaign for both starters thus far, I expect Sunday’s contest to deliver plenty of runs.
So, I’m looking toward the player prop markets.
Keller is really struggling, running a 4.89 ERA through 16 outings this season — it’s his worst season since 2021.
He’s also faced this Reds lineup more than a few times, as these teams are divisional rivals. So, we have a solid sample size to consider when handicapping this clash.
Reds vs Pirates Pick, Betting Analysis
Though Elly De La Cruz has just three hits across 19 head-to-head at-bats against Keller, I still think he’s in for a massive day at the plate.
Keller leans primarily on his four-seam fastball, which he throws over 32% of the time. He’s lost some stuff and velocity on the pitch over the past few years, leading to a steady decline in his swing-and-miss rate on the pitch.
While De La Cruz can be strikeout-prone, Keller doesn’t miss as many bats as he used to, which could hurt against an elite fastball slugger. De La Cruz has big-time power from both sides of the plate, especially when high-velocity pitches are left in the zone.
If De La Cruz can stay disciplined at the plate against Keller’s breaking stuff, he should see some hittable in-the-zone fastballs, cashing some props along the way.
Pick: Elly De La Cruz Over 1.5 HRR (-160)
