HomeRight ArrowMLB

Astros vs Nationals Prediction, Pick, MLB Odds for Monday, July 6

Astros vs Nationals Prediction, Pick, MLB Odds for Monday, July 6 article feature image
2 min read
Credit:

IMAGN IMAGES via Reuters Connect. Pictured: Yordan Alvarez

The Washington Nationals host the Houston Astros on July 6, 2026. First pitch from Nationals Park is scheduled for 6:45 p.m. EDT. The game will be broadcast on NATS.

The Astros are favored by -120 on the moneyline and by -1.5 on the run line. The Astros are -100 on the moneyline and -1.5 on the run line. The total is set at 10 runs.

Find my MLB picks and Astros vs Nationals prediction below, as well as probable pitchers, weather report, and more.


Header First Logo
Header Second Logo

Astros vs Nationals Prediction

  • Astros vs Nationals Pick: Over 10 (-110)

My Astros vs Nationals best bet is on the run total over. Make sure to find the best odds by checking our live MLB odds page.


Astros vs Nationals Odds

Astros Logo
July 6, 2026
6:45 p.m. EDT
NATS
Nationals Logo
Astros Odds
SpreadTotalMoneyline
-1.5
+155
10
-101o / -118u
-100
Nationals Odds
SpreadTotalMoneyline
-1.5
+155
10
-101o / -118u
-120
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Astros vs Nationals moneyline: Astros -100, Nationals -120
  • Astros vs Nationals over/under: 10 (-101o / -118u)
  • Astros vs Nationals spread: Astros -1.5 (+155), Astros -1.5 (+155)

Astros vs Nationals Probable Pitchers

RHP Mike Burrows (HOU)StatRHP Miles Mikolas (WSN)
4-8W-L2-7
-0.1fWAR (FanGraphs)-0.5
5.58/4.58ERA / xERA5.44/4.79
5.48/4.81FIP / xFIP5.38/4.56
9.8%K-BB%8.4%
37.5%GB%44.0%
.311BABIP.269
94Stuff+90
97Location+111

Header First Logo

Astros vs Nationals Pick, Betting Analysis

It's Yordan Alvarez vs. Miles Mikolas. The best hitter in the game this year against, arguably, the worst right-handed pitcher. But what are you going to do? Bet on Yordan Alvarez at +190 or whatever ridiculous line this will be set at? Are you a fish?

The simpler path is just to take the total. I don't think the books can comfortably price this one right. There have been 11.4 runs scored per game in DC this year. And now we get Mikolas hosting another horribly righty Mike Burrows. This is two of the worst pitching staffs in the league going up against two quite capable offenses.

I expected this total to be 11.5 or something; instead, we get 10. So I'm taking that as soon as I can! Look for the best lines, be smart, but this game is primed for a dozen dudes crossing home plate.

Pick: Over 10 (-110)

If you must bet homers and you're not super price-conscious, you can take the obvious parlay here. James Wood (+247) and Yordan Alvarez (+231) are #1 and #3 in my home run projections tonight (Hunter Goodman is #2).

They're both in elite spots against fly-ball righties and against bad bullpens behind them. The parlay there gives you a 10:1 return on your money on DraftKings. And you can find slightly better prices elsewhere if you're not a DK bettor.

Pick: James Wood and Yordan Alvarez HR Parlay (+900)


Astros vs Nationals Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author
Jon AndersonVerified Action Expert

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.