Red Sox vs. Guardians Odds & Betting Predictions - May 29, 2026

Red Sox at Guardians

11:10 pm • CLEG
@
Starting Pitchers
pitcherteameraw-l
Slade Cecconi logoS.CecconiCleveland Guardians logo5.183-5
Tyler Samaniego logoT.SamaniegoBoston Red Sox logo1.040-2

Red Sox at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Red Sox
23-32
+1.5
+1.5-200
o8-105
+109
Guardians
33-25
u7.5
-1.5+165
u8-115
-130
location pinFriday 11:10 p.m.
May 29, 2026
Progressive FieldCleveland
thermometer image73°Fahrenheit
rain image0%Rain
wind image8Wind
Red Sox vs. Guardians Expert Picks
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 74-96-9 (-8.4u)
CLE -115
1u
@Zerillo ⭐️⭐️⭐️ https://myaction.app/qxJUWRHux3b
Nick Martin
Nick Martin
Last 30d: 27-45-0 (-5.6u)
BOS +110
0.5u
RoyalsProps
RoyalsProps
Last 30d: 63-44-3 (+14.6u)
W.Contreras o1.5 Hits + Runs + RBIs-117
1.17u
Frank Ammirante
Frank Ammirante
Last 30d: 211-233-11 (-9.0u)
S.Cecconi o15.5 Outs-117
1.17u
CLE -118
1.18u
Sean Zerillo
Sean Zerillo
Last 30d: 177-144-12 (+7.8u)
CLE -120
0.6u
Bet to -133

Red Sox vs. Guardians Previews & Analysis

  • Red Sox vs Guardians: Zerillo's Pick for Friday article feature image

    Red Sox vs Guardians: Zerillo's Pick for Friday

    Sean Zerillo
    May 29, 2026 UTC
  • Adam Trigger's Triple-A Baseball Bets for Friday article feature image

    Adam Trigger's Triple-A Baseball Bets for Friday

    Adam Trigger
    May 29, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Red Sox vs. Guardians Public Betting Percentages

Away Logo

Red Sox

Public

33%

Bets%

67%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
31-2716-1215-1517-1714-10
Red Sox
21-349-1912-1514-226-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
28-3014-1414-1617-1711-13
Red Sox
25-28-29-17-216-1116-18-29-9

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
33-2516-1217-1320-1413-11
Red Sox
23-329-1914-1316-206-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 27thWSHW 3-2-1.5 LU 7.5CLE -180
May 26thWSHL 3-6-1.5 LO 7.5WSH -133
May 25thWSHL 2-10-1.5 LO 8.5WSH -174
May 24th@PHIW 3-1-1.5 WU 7CLE -115
May 23rd@PHIL 0-3+1.5 LU 7PHI +145

Red Sox vs. Guardians Injury Updates

Red Sox Injuries

  • Tanner Houck
    SP

    Houck is out with arm

    Out

  • Triston Casas
    1B

    Casas is out with knee

    Out

  • Patrick Sandoval
    SP

    Sandoval is out with elbow

    Out

  • Kutter Crawford
    SP

    Crawford is out with wrist

    Out

  • Romy Gonzalez
    1B

    Gonzalez is out with shoulder

    Out

Guardians Injuries

    Red Sox vs. Guardians Starting Lineups
    Red Sox Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Tyler Samaniego logoLT.Samaniego, P0-21.041.1546.75
    HITTERSAVGOBPSLGHR
    Jarren Duran logo1J.Duran, LF.213.279.3868
    Ceddanne Rafaela logo2C.Rafaela, CF.283.347.4405
    Wilyer Abreu logo3W.Abreu, RF.286.349.4336
    Willson Contreras logo4W.Contreras, 1B.286.381.51311
    Masataka Yoshida logo5M.Yoshida, DH.255.347.3631
    Mickey Gasper logo6M.Gasper, C.326.370.3720
    Nick Sogard logo7N.Sogard, 2B.273.368.3940
    Marcelo Mayer logo8M.Mayer, SS.218.278.2992
    Isiah Kiner-Falefa logo9I.Kiner-Falefa, 3B.300.382.3831
    Guardians Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Slade Cecconi logoRS.Cecconi, P3-55.181.4837.38
    HITTERSAVGOBPSLGHR
    Travis Bazzana logo1T.Bazzana, 2B.302.407.4583
    Jose Ramirez logo2J.Ramirez, 3B.226.343.3968
    Chase DeLauter logo3C.DeLauter, DH.260.342.4387
    Rhys Hoskins logo4R.Hoskins, 1B.189.335.3855
    Daniel Schneemann logo5D.Schneemann, CF.240.323.3844
    Angel Martinez logo6A.Martinez, RF.246.284.4589
    Brayan Rocchio logo7B.Rocchio, SS.298.379.4214
    Patrick Bailey logo8P.Bailey, C.120.185.2801
    Petey Halpin logo9P.Halpin, LF.120.154.1200

    Red Sox vs. Guardians Odds Comparison

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    Red Sox at Guardians Team Totals

    MatchupOverUnder
    Red Sox
    23-32
    N/A
    N/A
    Guardians
    33-25
    N/A
    N/A