Astros vs. Twins Odds & Betting Predictions - May 20, 2026

Astros at Twins

5:40 pm • MNNT
1 - 4
Starting Pitchers
pitcherteameraw-l
Joe Ryan logoJ.RyanMinnesota Twins logo3.023-3
Mike Burrows logoM.BurrowsHouston Astros logo5.752-6

Astros at Twins Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
20-31
+1.5
+1.5-181
o7.5-114
+115
Twins
23-27
u8.5
-1.5+146
u7.5-105
-136
location pinWednesday 5:40 p.m.
May 20, 2026
Target FieldMinneapolis
Astros vs. Twins Expert Picks
Picks Office
Picks Office
Last 30d: 167-175-12 (-18.1u)
HOU +130 (Live)
1u
Pre Game Line Join Discord for earlier access: https://discord.gg/HjKxYKdSUy Houston is 2-8 in its last 10, so the price is ugly for a reason. The buy point is still the middle: Yordan is confirmed third with a 1.0381393 OPS, 15 HR, and 31 RBI, with Walker behind him at 11 HR and 31 RBI. Houston just beat Minnesota 2-1 yesterday. At +130, I only need one messy game.
💰🦡 Jake
💰🦡 Jake
Last 30d: 60-63-5 (+7.6u)
MIN -0.5 (F5)-110
1.5u
Markus Markets
Markus Markets
Last 30d: 51-39-0 (+5.4u)
J.Ryan u1.5 BB+112
1u
Ryan Minion
Ryan Minion
Last 30d: 357-360-13 (+60.3u)
Y.Alvarez o1.5 Total Bases+100
$1.00
B.Buxton o1.5 Total Bases-104
$1.04
Grant Neiffer
Grant Neiffer
Last 30d: 31-111-8 (+7.4u)
Y.Alvarez o0.5 HR+414
0.25u
Austin Pendergrass
Austin Pendergrass
Last 30d: 35-23-0 (+2.3u)
Under 8.5-132
0.38u
Frank Ammirante
Frank Ammirante
Last 30d: 264-274-11 (-2.4u)
HOU u3.5-120
1u
Sean Zerillo
Sean Zerillo
Last 30d: 172-146-12 (+4.5u)
Under 8.5-124
0.5u
Bet to 7.5 (-105)

Astros vs. Twins Previews & Analysis

  • Grant's 5 Home Run Bets for Wednesday article feature image

    Grant's 5 Home Run Bets for Wednesday

    Grant Neiffer
    May 20, 2026 UTC
  • Our Over/Under Projection for Astros vs Twins article feature image

    Our Over/Under Projection for Astros vs Twins

    Action Network Staff
    May 20, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Twins Public Betting Percentages

Away Logo

Astros

Public

26%

Bets%

74%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Twins
26-2417-129-127-719-16
Astros
20-3111-159-164-1116-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Twins
27-19-414-11-413-87-6-119-13-3
Astros
27-20-416-9-111-11-39-617-14-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Twins
23-2715-148-136-817-18
Astros
20-3112-148-175-1015-20

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 19thHOUL 1-2-1.5 LU 8.5HOU -136
May 18thHOUW 6-3-1.5 WU 9MIN -115
May 17thMILW 5-4+1.5 WO 8MIN +118
May 16thMILL 1-2+1.5 WU 8.5MIL +110
May 15thMILL 2-3+1.5 WU 8.5MIL -110

Twins vs. Astros Injury Updates

Twins Injuries

  • Pablo Lopez
    SP

    Lopez is out with elbow

    Out

  • David Festa
    SP

    Festa is out with shoulder

    Out

  • Travis Adams
    SP

    Adams is out with triceps

    Out

Astros Injuries

  • Lance McCullers
    SP

    Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.

    Out

Astros vs. Twins Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Mike Burrows logoRM.Burrows, P88624
AJ Blubaugh logoRA.Blubaugh, P13110
Nate Pearson logoRN.Pearson, P11100
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS1-4000
Isaac Paredes logo2I.Paredes, 3B0-4000
Yordan Alvarez logo3Y.Alvarez, DH0-4000
Christian Walker logo4C.Walker, 1B0-4000
Jake Meyers logo5J.Meyers, CF0-4000
Zach Dezenzo logo6Z.Dezenzo, LF1-3100
Brice Matthews logo7B.Matthews, 2B0-3000
Cam Smith logo8C.Smith, RF2-3000
Christian Vazquez logo9C.Vazquez, C1-2001
Zach Cole logo9Z.Cole, PH0-1000
Cesar Salazar logo9C.Salazar, C0-0000
Twins Player Stats
Projected
PITCHERPCIPKER
Joe Ryan logoRJ.Ryan, P99691
Yoendrys Gomez logoRY.Gomez, P36250
Andrew Morris logoRA.Morris, P10110
HITTERSH-ABRHRRBI
Byron Buxton logo1B.Buxton, DH0-3000
Trevor Larnach logo2T.Larnach, LF0-4000
Josh Bell logo3J.Bell, 1B0-3000
Austin Martin logo3A.Martin, RF0-0000
Kody Clemens logo4K.Clemens, RF1-4000
Kody Clemens logo4K.Clemens, 1B1-4000
Luke Keaschall logo5L.Keaschall, 2B0-4000
Victor Caratini logo6V.Caratini, C2-4211
Tristan Gray logo7T.Gray, 3B1-1100
Ryan Kreidler logo8R.Kreidler, SS1-3113
James Outman logo9J.Outman, CF1-3000

Astros vs. Twins Odds Comparison

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Astros at Twins Team Totals

MatchupOverUnder
Astros
20-31
N/A
N/A
Twins
23-27
N/A
N/A