The Minnesota Twins (65-84) and New York Yankees (83-66) will face off in the MLB tonight. First pitch from Target Field is scheduled for 7:40 p.m. ET. The game will broadcast live on YES.
New York is a -190 favorite to win outright on the moneyline, while Minnesota is +160 to pull off the upset. The over/under is set at 9 total runs.
Continue below for my Yankees vs Twins predictions and MLB picks for Monday, September 15, as well as probable pitchers, betting trends, injury reports and more.
My Yankees vs Twins Prediction
- Yankees vs Twins pick: Yankees Moneyline (-190)
My Twins vs. Yankees best bet is on New York moneyline, with the best price currently available at bet365. But as always, make sure to find the best odds by checking our live MLB odds page.
Yankees vs Twins Odds
| Yankees Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -120 | 9 -115o / -105u | -190 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +100 | 9 -115o / -105u | +160 |
Yankees vs Twins Preview, Picks
This system isolates profitable late-season road favorites playing in high-humidity environments, which appears to be the case for the Yankees in tonight's matchup against the Twins.
By targeting teams with strong underlying performance (Pythagorean Win % 55–69%) and favorable odds late in the season (Game 121–159), playoff-contending teams are often undervalued against weaker opponents.
High humidity (70–100%) can increase offensive output, especially favoring superior teams with more depth.
Road favorites tend to be mispriced due to travel fatigue bias despite actual team quality and momentum.
This strategy exploits undervaluation in humid environments where sharp teams can "hammer" through fatigue and softer opponents.
Yankees vs Twins Best Bet
- Yankees ML (-190)
