The St. Louis Cardinals host the Washington Nationals on July 10, 2025. First pitch from Busch Stadium is scheduled for 7:45 p.m. EDT; the game will be broadcast on MASN.
Find my MLB betting preview and Nationals vs Cardinals prediction below, as well as probable pitchers, betting trends, injury reports and more.
Prop Model's Nationals vs Cardinals Prediction
- Nationals vs Cardinals picks: James Wood Over 1.5 Total Bases (+115)
My Nationals vs Cardinals best bet is for James Wood to record Over 1.5 Total Bases. Make sure to find the best odds by checking our live MLB odds page.
Nationals vs Cardinals Odds
| Nationals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +145 | 9 -119o / -106u | +119 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -175 | 9 -119o / -106u | -141 |
Nationals vs Cardinals Preview
The Nationals and Cardinals have split the first two games of this series and are each 4-6 over their past 10. However, the Cardinals have been the better team over the course of the season as they are five games over .500. Meanwhile, Washington is 16 games under .500 and has a -82 run differential.
As a result, the Cardinals are appropriately priced as the favorite in this matchup. However, the best Nationals vs. Cardinals betting value comes to us via the prop markets.
James Wood, who is hitting .287 with 24 homers this season, has hits in three straight games and homered on Wednesday night. Wood is having a strong season at the plate and there's value in backing him to continue performing on Thursday night.
Nationals vs Cardinals Prediction, Betting Analysis
The total bases prop for James Wood looks like a strong over wager based on the current data. The line of 1.5 compares favorably based on our MLB simulations. The prop projects to hit 53.21% of the time based on the assumptions, and that represents a 5.59% edge. You can find all prop bet evaluations in ParlayIQ.
Pick: James Wood Over 1.5 Total Bases
Moneyline
I don't see any value in the Nationals vs. Cardinals moneyline.
Run Line (Spread)
I'm going to pass on the Nationals vs. Cardinals run line.
Over/Under
I'm not betting on the Nationals vs. Cardinals over/under.
Nationals vs Cardinals Betting Trends
Nationals vs Cardinals Weather
