Cincinnati vs. Clemson Odds & Betting Predictions - December 21, 2025
Cincinnati at Clemson
8:00 pm • ESPNCincinnati at Clemson Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Cincinnati 7-5 | +6.5 | +4-110 | o140.5-108 | +154 |
Clemson 10-3 | u137.5 | -4-110 | u140.5-110 | -185 |

Bon Secours Wellness ArenaGreenville
Cincinnati vs. Clemson Expert Picks
CTO
Last 30d: 20-18-0 (+2.6u)
CIN +5.5-105
0.95u
Cincinnati vs. Clemson Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Cincinnati vs. Clemson Public Betting Percentages
Betting Trends
- Clemson are 3-2 in their last 5 games.
- Clemson are 2-3 in their last 5 games against the spread
- Clemson are 3-1 in their road games against the spread
- The totals have gone OVER in 1 of Clemson' last 5 games
- The totals have gone OVER in 3 of Clemson' 9 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-7 | 3-6 | 3-1 | 4-7 | 2-0 | |
| 4-8 | 3-6 | 1-2 | 3-4 | 1-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 6-7 | 3-6 | 3-1 | 5-6 | 1-1 | |
| 3-9 | 2-7 | 1-2 | 1-6 | 1-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 10-3 | N/A | N/A | 10-1 | 0-2 | |
| 7-5 | N/A | N/A | 6-1 | 0-4 |
Last 5 Matchups
Team Stats
22-58 (38%)
Field Goals
24-50 (48%)
11-15 (73%)
Free Throws
10-14 (71%)
10-25 (40%)
3P
10-20 (50%)
33
Rebounds
23
9
Assists
15
12
Turnovers
12
5
Steals
6
4
Blocks
1
13
Fouls
12
Cincinnati vs. Clemson Odds Comparison
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Cincinnati at Clemson Team Totals
MatchupOverUnder | ||
|---|---|---|
Cincinnati 7-5 | o68.5-110 | u68.5-120 |
Clemson 10-3 | o72.5-115 | u72.5-115 |



