The Portland Trail Blazers (8-13) and Cleveland Cavaliers (13-9) will face off in the NBA tonight. Tipoff is set for 7:00 p.m. EST from Rocket Arena in Cleveland, Ohio. The game will broadcast live on KUNP.
The Cavaliers are 10-point favorites over the Blazers on the spread (Cavaliers -10), with the over/under set at 240.5 total points. Cleveland is a -500 favorite to win outright on the moneyline, while Portland is +375 to pull off the upset.
Let's get into my Trail Blazers vs. Cavaliers predictions and NBA picks for Wednesday, December 3.
- Trail Blazers vs Cavaliers pick: Over 240.5 (-110)
My Trail Blazers vs Cavaliers best bet is on the over, with the best price currently available at bet365. But as always, make sure to find the best odds by checking our live NBA odds page.
Trail Blazers vs Cavaliers Odds
| Trail Blazers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+10 -115 | 240.5 -110o / -110u | +375 |
| Cavaliers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-10 -105 | 240.5 -110o / -110u | -500 |
Trail Blazers vs Cavaliers NBA Preview
The Trail Blazers head into this matchup after suffering a third consecutive loss (121-118 vs. Toronto), adding even more weight to their rough stretch in the Western Conference.
The main issue for the Trail Blazers continues to be dealing with their guard rotation.
Injuries keep piling up, and after missing yesterday’s game against Toronto, Matisse Thybulle (thumb) is now listed as questionable for tonight.
Thybulle joins a long injury list headlined by Dame Lillard, Scoot Henderson, Jrue Holiday, and Blake Wesley.
Perimeter defense will be the key factor tonight against the Cavaliers, which puts the spotlight on Shaedon Sharpe, who — being the team’s leader in steals (1.4 per game) — is Portland’s best hope to keep Cleveland in check.
On the other side of the court, the Cavaliers come into tonight’s game in a completely different situation.
After crushing the Pacers 135-119, Kenny Atkinson’s Cavs will look to keep climbing the standings in the East.
Cleveland’s medical staff has confirmed that Max Strus (foot) and Sam Merrill (hand) have been ruled out for tonight’s matchup; meanwhile, Lonzo Ball (illness) is still listed as probable, so he’s expected to log minutes in the rotation.
As mentioned before, the perimeter will be the key in this game, and the Cavs’ efficiency from outside could quickly dictate the pace of the matchup.
Donovan Mitchell, Darius Garland, and De’Andre Hunter will be crucial from beyond the arc, while Evan Mobley becomes the central piece in the paint with Jarrett Allen (finger) sidelined.
Trail Blazers vs Cavaliers Prediction, Betting Analysis
The NBA system titled "Bad Road Overs" focuses on games where struggling road teams face stronger home opponents in non-conference matchups, creating favorable conditions for high-scoring results.
When a poor road team with a low win rate meets a winning home team, defensive effort and intensity often dip for the visitor while the home side pushes the pace and controls offensive rhythm.
Non-conference games tend to feature looser defensive schemes and unfamiliar matchups, leading to faster scoring runs and less resistance in transition.
The data shows that when totals close above the 220 range and the line movement slightly favors the Over, the market correctly anticipates offensive efficiency rather than defensive pressure.
These situations consistently produce games where both teams exceed expectations, with the stronger home team dictating tempo and the weaker visitor contributing enough to push the total past the number
Pick: Over 240.5 (-110)
Spread
We don't see value in the spread tonight.
Moneyline
No play on the moneyline.
Over/Under
As mentioned, Evan Abrams' system fits perfectly for this game, so we're backing the Over tonight.
Cavaliers vs Trail Blazers Betting Trends



















